Labels:text | screenshot | black and white | black | font | document | monochrome OCR: tumours Approximately fifteen per cent of pituita bre are usually associated with gigantism bel physial epiphysial fusion or acromegaly after ep fusion. Acromegaly is the more common cur most manifestation since pituitary tumours o in frequently in middle age and only rarely omas, childhood. Large tumours or macroader GH, are particularly those secreting prolactin and e surgical often locally invasive, rendering comple uitary removal difficult or impossible. Many pi r example, tumours have mixed cell populations; f ciated somatotroph and lactotroph cells are ass prolactin. with increased secretion of both GH and same cell isWith mixed-cell tumours, however, the nes. only rarely found to contain both horm
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